2009/2008 | 2007 | 2005/2006 | 2003/2004 | 2001/2002 | 1999/2000 | 1997/98 | Up to 1997
An aspartate and a water molecule mediate efficient acid-base catalysis in a tailored antibody pocket
Debler, E. W., Müller, R., Hilvert, D., and Wilson, I. A., Proc. Natl. Acad. Sci. U. S. A. 2009, 18539-18550Kinetic characterization of spiropyrans in aqueous media
Stafforst, T., and Hilvert, D. Chem. Commun. 2009, 287-288A rationally designed aldolase foldamer
Müller, M. M., Windsor, M. A., Pomerantz, W. C., Gellman, S. H., and Hilvert, D., Angew. Chem., Int. Ed. Engl. 2009, 48, 922-925.Probing the role of the proximal heme ligand in cytochrome P450cam by recombinant incorporation of selenocysteine
Aldag, C., Gromov, I. A., Garcia-Rubio, I., Von Koenig, K., Schlichting, I., Jaun, B., and Hilvert, D. 2009 , Proc. Natl. Acad. Sci. U. S. A. 106, 5481-5486.
Relative tolerance of an enzymatic molten globule and its thermostable counterpart to point mutation
Woycechowsky, K. J., Choutko, A., Vamvaca, K., and Hilvert, D. 2008 , Biochemistry 47, 13489-13496.Structural reorganization and preorganization in enzyme active sites: Comparisons of experimental and theoretically ideal active site geometries in the multistep serine esterase reaction cycle
Smith, A. J. T., Müller, R., Toscano, M. D., Kast, P., Hellinga, H. W., Hilvert, D., and Houk, K. N. 2008 , J. Am. Chem. Soc. 130, 15361-15373.Synthesis of β-hydroxy-α-amino acids with a reengineered alanine racemase
Fesko, K., Giger, L., and Hilvert, D. Bioorganic and Medicinal Chemistry Letters 2008Protein design by directed evolution
Jäckel, C., Kast, P., and Hilvert, D. Annual review of biophysics 2008 37, 153-173De novo computational design of retro-aldol enzymes
Jiang, L., Althoff, E. A., Clemente, F. R., Doyle, L., Röthlisberger, D., Zanghellini, A., Gallaher, J. L., Betker, J. L., Tanaka, F., Barbas Iii, C. F., Hilvert, D., Houk, K. N., Stoddard, B. L., and Baker, D.Science 2008 319, 1387-1391On the relationship between folding and chemical landscapes in enzyme catalysis
Roca, M., Messer, B., Hilvert, D., and Warshel, A. Proc. Natl. Acad. Sci. U. S. A. 2008 105, 13877-13882Kinetics and Thermodynamics of Ligand Binding to a Molten Globular Enzyme and Its Native Counterpart
Vamvaca, K., Jelesarov, I., and Hilvert, D. J. Mol. Biol. 2008 382, 971-977Closely related antibody receptors exploit fundamentally different strategies for steroid recognition
Verdino, P., Aldag, C., Hilvert, D., and Wilson, I. A. Proc. Natl. Acad. Sci. U. S. A. 2008 105, 11725-11730Catalysis of oxidative protein folding by small-molecule diselenides.
Beld, J., K. J. Woycechowsky, et al. Biochemistry 2008 47(27): 6985-6987.
Selenoglutaredoxin as a glutathione peroxidase mimic.
Casi, G., G. Roelfes, et al. ChemBioChem 2008 9(10): 1623-1631.
Conformational isomerism can limit antibody catalysis.
Debler, E. W., R. Muller, et al. Journal of Biological Chemistry 2008 283(24): 16554-16560.
De novo computational design of retro-aldol enzymes.
Jiang, L., E. A. Althoff, et al. Science 2008 319(5868): 1387-1391.
Switching antibody specificity through minimal mutation.
Piatesi, A., C. Aldag, et al. Journal of Molecular Biology 2008 377(4): 993-1001.
The putative Diels-Alderase macrophomate synthase is an efficient aldolase.
Serafimov, J. M., D. Gillingham, et al. Journal of the American Chemical Society 2008 130(25): 7798.
Reinvestigation of a selenopeptide with purportedly high glutathione peroxidase activity
Casi, G. & Hilvert, D. Journal of Biological Chemistry 2007 282 (42): 30518-30522Structure and dynamics of a molten globular enzyme.
Pervushin, K., K. Vamvaca, et al. Nature Structural & Molecular Biology 2007 14: 1202-1206.Metabolic engineering of a genetic selection system with tunable stringency
Kleeb, A.C., Edalat, M.H., Gamper, M., Haugstetter, J., Giger, L., Neuenschwander, M., Kast, P., Hilvert, D. Proceedings of the National Academy of Sciences of the United States of America 2007 104 (35), pp. 13907-13912A simple selection strategy for evolving highly efficient enzymes
Neuenschwander, M., Butz, M., Heintz, C., Kast, P., Hilvert, D. Nature Biotechnology 2007 25 (10), pp. 1145-1147Preparation of the β3-homoselenocysteine derivatives Fmoc-β3hSec(PMB)-OH and Boc-β3hSec(PMB)-OH for solution and solid-phase-peptide synthesis and selenoligation
Flögel, O., Casi, G., Hilvert, D., Seebach, D. Helvetica Chimica Acta 2007 90 (9), pp. 1651-1666Trapping and structural elucidation of an intermediate in the macrophomate synthase reaction pathway
Serafimov, J.M., Westfeld, T., Meier, B.H., Hilvert, D.Journal of the American Chemical Society 2007 129 (31), pp. 9580-9581,Minimalist active-site redesign: Teaching old enzymes new tricks
Toscano, M.D., Woycechowsky, K.J., Hilvert, D., Angewandte Chemie - International Edition 2007 46 (18), pp. 3212-3236Enhancing activity and controlling stereoselectivity in a designed PLP-dependent aldolase
Toscano, M.D., Müller, M.M., Hilvert, D., Angewandte Chemie - International Edition 2007 46 (24), pp. 4468-4470Selenoglutathione: Efficient oxidative protein folding by a diselenide,
Beld, J., Woycechowsky, K.J., Hilvert, D., Biochemistry 2007 46 (18), pp. 5382-5390Active site mutagenesis of the putative Diels-Alderase macrophomate synthase,
Serafimov, J.M., Lehmann, H.C., Oikawa, H., Hilvert, D., Chemical Communications 2007 (17), pp. 1701-1703Relative tolerance of mesostable and thermostable protein homologs to extensive mutation,
Besenmatter, W., Kast, P., Hilvert, D., Proteins: Structure, Function and Genetics 2007 66 (2), pp. 500-506Synthesis and application of an azobenzene amino acid as a light-switchable turn element in polypeptides,
Aemissegger, A., Hilvert, D., Nature Protocols 2007 2 (1), pp. 161-167Bifunctional catalysis of proton transfer at an antibody active site
Müller, R., Debler, E.W., Steinmann, M., Seebeck, F.P., Wilson, I.A., Hilvert, D., Journal of the American Chemical Society 2007 129 (3), pp. 460-461Novel enzymes through design and evolution
Woycechowsky, K.J., Vamvaca, K., Hilvert, D., Advances in Enzymology and Related Areas of Molecular Biology 2007 75, pp. 241-294, 2007
A monofunctional and thermostable prephenate dehydratase from the archaeon Methanocaldococcus jannaschii (vol 45, pg 14101, 2006).
Kleeb, A. C.; Kast, P.; Hilvert, D.,Biochemistry 2007, 46, (9), 2552-2552.
A monofunctional and thermostable prephenate dehydratase from the archaeon Methanocaldococcus jannaschii
Kleeb, A. C.; Kast, P.; Hilvert, D.Biochemistry 2006, 47, 14101
Stereoselectivity and expanded substrate scope of an engineered PLP-dependent aldolase
Seebeck, F. P.; Guainazzi, A.; Amoreira, C.; Baldridge, K. K.; Hilvert, D.Angewandte Chemie-International Edition 2006, 45, 6824
A photoswitchable miniprotein based on the sequence of avian pancreatic
Jurt, S.; Aemissegger, A.; Guntert, P.; Zerbe, O.; Hilvert, D.Angewandte Chemie-International Edition 2006, 45, 6297
Tunnel plasticity and quaternary structural integrity of a pentameric protein ring.
K. J. Woycechowsky, F. P. Seebeck, D. Hilvert, Protein Science 2006, 15, 1106.
A simple tagging system for protein encapsulation.
F. P. Seebeck, K. J. Woycechowsky, W. Zhuang, J. P. Rabe, D. Hilvert, Journal Of The American Chemical Society 2006, 128, 4516.
Experimental and computational investigation of the uncatalyzed rearrangement and elimination reactions of isochorismate.
M. S. DeClue, K. K. Baldridge, P. Kast, D. Hilvert, Journal Of The American Chemical Society 2006, 128, 2043.An active enzyme constructed from a 9-amino acid alphabet.
K. U. Walter, K. Vamvaca, D. Hilvert, Journal Of Biological Chemistry 2005, 280, 37742.
Isochorismate pyruvate lyase: A pericyclic reaction mechanism?
M. S. DeClue, K. K. Baldridge, D. E. Kunzler, P. Kast, D. Hilvert, Journal Of The American Chemical Society 2005, 127, 15002.
Mechanistic insights into the isochorismate pyruvate lyase activity of the catalytically promiscuous PchB from combinatorial mutagenesis and selection.
D. Kunzler, S. Sasso, M. Gamper, D. Hilvert, P. Kast, Journal Of Biological Chemistry 2005, 280, 32827.
Isotope effects on the enzymatic and nonenzymatic reactions of chorismate.
S. K. Wright, M. S. DeClue, A. Mandal, L. Lee, O. Wiest, W. W. Cleland, D. Hilvert, Journal Of The American Chemical Society 2005, 127, 12957.
Conformational diversity and catalysis.
D. Hilvert, Biopolymers 2005, 80, 492.
Simultaneous optimization of enzyme activity and quaternary structure by directed evolution.
K. Vamvaca, M. Butz, K. U. Walter, S. V. Taylor, D. Hilvert, Protein Science 2005, 14, 2103.
Conformational diversity and catalysis.
D. Hilvert, Faseb Journal 2005, 19, A249.
Investigation of ligand binding and protein dynamics in Bacillus subtilis chorismate mutase by transverse relaxation optimized spectroscopy-nuclear magnetic resonance.
A. Eletsky, A. Kienhofer, D. Hilvert, K. Pervushin, Biochemistry 2005, 44, 6788.
Strategy for chromosomal gene targeting in RecA-deficient Escherichia coli strains.
M. Gamper, P. Kast, Biotechniques 2005, 38, 405.
Structural origins of efficient proton abstraction from carbon by a catalytic antibody.
Debler, E.W.; Ito, S.; Seebeck, F.P.; Heine, A.; Hilvert, D.; Wilson, I.A. Proc. Natl. Acad. Sci. USA, 2005, 102, 4984-4989.
Use of molecular dynamics in the design and structure determination of a photoinducible beta-hairpin.
Krautler, V; Aemissegger, A.; Hunenberger, P.H.; Hilvert, D.; Hansson, T.; van Gunsteren, W.F. J. Am. Chem. Soc., 2005, 127, 4935-4942.
A photoinducible beta-hairpin.
Aemissegger, A.; Krautler, V.; van Gunsteren, W.F.; Hilvert, D. J. Am. Chem. Soc., 2005, 127, 2929-2936.
Characterization of the secreted chorismate mutase from the pathogen Mycobacterium tuberculosis.
Sasso, S.; Ramakrishnan, C.; Gamper, M.; Hilvert, D.; Kast, P. FEBS J., 2005, 272, 375-389.
Positional ordering of reacting groups contributes significantly to the efficiency of proton transfer at an antibody active site.2003/2004
Seebeck, F.P; Hilvert, D. J. Am. Chem. Soc., 2005, 127, 1307-1312.
New enzymes from combinatorial library modules
Besenmatter, W.; Kast, P.; Hilvert, D. Methods Enzymol., 2004, 388, 91-102.
An enzymatic molten globule: Efficient coupling of folding and catalysis
Vamvaca, K.; Vogeli, B.; Kast, P.; Pervushin, K.; Hilvert, D. Proc. Natl. Acad. Sci. USA, 2004, 101, 12860-12864.
Nonspecific medium effects versus specific group positioning in the antibody and albumin catalysis of the base-promoted ring-opening reactions of benzisoxazoles
Hu, Y.F.; Houk, K.N.; Kikuchi, K.; Hotta, K.; Hilvert, D. J. Am. Chem. Soc., 2004, 126, 8197-8205.
Deciphering enzymes - Genetic selection as a probe of structure and mechanism.
Woycechowsky, K.; Hilvert, D. Eur. J. Biochem., 2004, 271, 1630-1637.
Immunological optimization of a generic hydrophobic packet for high affinity hapten binding and Diels-Alder activity.
Piatesi, A.; Hilvert, D. ChemBioChem, 2004, 5, 460-466.
Quantitative evaluation of noncovalent chorismate mutase-inhibitor binding by ESI-MS.
Wendt, S.; McCombie, G.; Daniel, J.; Kienhöfer, A.; Hilvert, D.; Zenobi, R. J. Amer. Soc. Mass. Spectrom., 2003, 14, 1470-1476.
Convergent protein synthesis.
Casi, G.; Hilvert, D. Curr. Opin. Struct. Biol., 2003, 13, 589-594.
Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation.
Seebeck, F.; Hilvert, D. J. Am. Chem. Soc., 2003, 125, 10158-10159.
Incorporation of selenomethionine into proteins through selenohomocysteine-mediated ligation.
Roelfes, G.; Hilvert, D. Angew. Chem. Int. Ed., 2003, 42, 2275-2277.
Promiscuity in antibody catalysis: Esterolytic activity of the decarboxylase 21D8.
Backes, A.; Hotta, K.; Hilvert, D. Helv. Chim. Acta, 2003, 86, 1167-1174.
Charge optimization increases the potency and selectivity of a chorismate mutase inhibitor.
Mandal, A.; Hilvert, D. J. Am. Chem. Soc., 2003, 125, 5598-5599.
Selective stabilization of the chorismate mutase transition state by a positively charged hydrogen bond donor.
Kienhöfer, A.; Kast, P.; Hilvert, D. J. Am. Chem. Soc., 2003, 125, 3206-3207.
Catalysis on the coastline: Theozyme, molecular dynamics, and free energy perturbation analysis of antibody 21D8 catalysis of the decarboxylation of 5-nitro-3-carboxybenzisoxazole.2001/2002
Ujaque, G.; Tantillo, D.J.; Hu, Y.F.; Houk, K.N.; Hotta, K.; Hilvert, D. J. Comput. Chem., 2003, 24, 98-110.
Steric and electronic effects on an antibody-catalyzed Diels-Alder reaction.
Gozin, Y.; Hilvert, D. Helv. Chim. Acta, 2002, 85, 4328-4336.
Selenocysteine-mediated backbone cyclization of unprotected peptides followed by alkylation, oxidative elimination or reduction of the selenol.
Quaderer, R.; Hilvert, D. Chem. Commun., 2002, 2620-2621.
Direct NMR observation and DFT calculations of a hydrogen bond at the active site of a 44 kDa enzyme.
Eletsky, A.; Heinz, T.; Moreira, O.; Kienhöfer, A.; Hilvert, D.; Pervushin, K. J. Biomol. NMR, 2002, 24, 31-39.
An antibody that reconstitutes the "base-on" form of B12 coenzymes.
Hannak, R.B.; Konrat, R.; Schüler, W.; Kräutler, B.; Auditor, M.T.M.; Hilvert, D. Angew. Chem. Int. Ed., 2002, 41, 3613-3616.
Investigation of the enzymatic and nonenzymatic cope rearrangement of carbaprephenate to carbachorismate.
Aemissegger, A.; Jaun, B.; Hilvert, D. J. Org. Chem., 2002, 67, 6725-6730.
Optimized production of the Diels-Alderase antibody 1E9 as a chimeric Fab.
Piatesi, A.; Hilvert, D. Can. J. Chem., 2002, 80, 657-664.
Synthesis of b3-peptides and mixed a/b3-peptides by thioligation.
Kimmerlin, T.; Seebach, D.; Hilvert, D. Helv. Chim. Acta, 2002, 85, 1812-1826.
Probing ligand recognition in the decarboxylase antibody 21D8: Implications for the catalytic mechanism.
Hotta, K.; Wilson, I. A.; Hilvert, D. Biochemistry, 2002, 41, 772-779.
Improved synthesis of C-terminal peptide thioesters on "safety-catch" resins using LiBr/THF.
Quaderer, R.; Hilvert, D. Org. Letters, 2001, 3, 3181-3184.
Investigating and engineering enzymes by genetic selection.
Taylor, S. V.; Kast, P.; Hilvert, D. Angew. Chem. Int. Ed., 2001, 40, 3310-3335.
Fmoc-compatible solid-phase peptide synthesis of long C-terminal peptide thioesters.
Sewing, A.; Hilvert, D. Angew. Chem. Int. Ed., 2001, 40, 3395.
Searching sequence space for protein catalysts.
Taylor, S. V.; Walter, K. U.; Kast, P.; Hilvert, D. Proc. Natl. Acad. Sci. USA, 2001, 98, 10596-10601.
Selenocysteine-mediated native chemical ligation.
Quaderer, R.; Sewing, A.; Hilvert, D. Helv. Chim. Acta, 2001, 84, 1197-1206.
Chemical biology/biological chemistry.
Hilvert, D. Chimia, 2001, 55, 267.
Cross-fertilizing the chemical field.1999/2000
Hilvert, D. C&E News, 2001, 79, 152.
Shape complementarity, binding-site dynamics, and transition state stabilization: A theoretical study of Diels-Alder catalysis by antibody 1E9.
Chen J. G.; Deng Q.L.; Wang R. X.; Houk, K. N.; Hilvert, D. Chembiochem, 2000, 1, 255-261.
A strategically positioned cation is crucial for efficient catalysis by chorismate mutase.
Kast, P.; Grisostomi, C.; Chen, I. A.; Li, S. L.; Krengel, U.; Xue, Y. F.; Hilvert, D. J. Biol. Chem., 2000, 275, 36832-36838.
Probing the role of the C-terminus of Bacillus subtilis chorismate mutase by a novel random protein-termination strategy.
Gamper, M.; Hilvert, D.; Kast, P. Biochemistry, 2000, 39, 14087-14094.
Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: Crystal structures of abzyme 21D8.
Hotta, K.; Lange, H.; Tantillo, D. J.; Houk, K. N.; Hilvert, D.; Wilson, L. A. J. Mol. Biol., 2000, 302, 1213-1225.
Catalysis of 3-carboxy-1,2-benzisoxazole decarboxylation by hydrophobic antibody binding pockets.
Hotta, K.; Kikuchi, K.; Hilvert, D. Helv. Chim. Acta, 2000, 83, 2183-2191.
Critical analysis of antibody catalysis.
Hilvert, D. Annu. Rev. Biochem., 2000, 69, 751-793.
Characterization of proton-transfer catalysis by serum albumins.
Hollfelder, F.; Kirby, A. J.; Tawfik, D. S.; Kikuchi, K.; Hilvert, D. J. Am. Chem. Soc., 2000, 122, 1022-1029.
Facile, Fmoc-compatible solid-phase synthesis of peptide C-terminal thioesters.
Swinnen, D.; Hilvert, D. Org. Lett., 2000, 2, 2439-2442.
Molecular dynamics simulations highlight mobile regions in proteins: A novel suggestion for converting a murine Vh domain into a more traceable species.
Voordijk, S.; Hansson, T.; Hilvert, D.; van Gunsteren, W. F. J. Mol. Biol., 2000, 300, 963-973.
Catalysis of decarboxylation by a preorganized heterogeneous microenvironment: crystal structures of abzyme 21D8.
Hotta, K.; Lange, H.; Tantillo, D.; Houk, K. N.; Hilvert, D.; Wilson, I. A. J. Mol. Biol., 2000, 302, 1213-1225.
Catalysis of 3-carboxy-1,2-benzisoxazole decarboxylation by hydrophobic antibody binding pockets.
Hotta, K.; Kikuchi, K.; Hilvert, D. Helv. Chim. Acta, 2000, 83, 2183-2191.
Shape complementarity, binding-site dynamics, and transition state stabilization: A theoretical study of Diels-Alder catalysis by antibody 1E9.
Chen, J.; Deng, Q.; Wang, R.; Houk, K. N.; Hilvert, D. ChemBioChem, 2000, 1, 255-261.
A strategically positioned cation is crucial for efficient catalysis by chorismate mutase.
Kast, P.; Grisostomi, C.; Chen, I. A.; Li, S.; Krengel, U.; Xue, Y.; Hilvert, D. J. Biol. Chem., 2000, 275, 36832-36838.
Probing the role of the C-terminus of Bacillus subtilis chorismate mutase by a novel random protein-termination strategy.
Gamper, M.; Hilvert, D.; Kast, P. Biochemistry, 2000, 39, 14087-14094.
Chorismate Mutase from Bacillus subtilis is partially diffusion controlled.
Mattei, P.; Kast, P.; Hilvert, D. Eur. J. Biochem., 1999, 261, 25-32.
Chemoenzymatic synthesis of isotopically labeled chorismic acids.
Gustin, D. J.; Hilvert, D.; J. Org. Chem., 1999, 64, 4935-4938.
Catalysis by antibodies.
Hilvert, D. in Comprehensive Natural Products Chemistry 1999. Volume 5: Enzymes, Enzyme Mechanisms, Proteins and Aspects of NO Chemistry; Elsevier: Oxford, UK; 1999.
Heavy atom isotope effects reveal a highly polarized transition state for chorismate mutase.
Gustin, D. J.; Mattei, P.; Kast, P.; Wiest, O.; Lee, L.; Cleland, W. W.; Hilvert, D. J. Am. Chem. Soc., 1999, 121, 1756-1757.
a-Functionalized phosphonyl-phosphinates: Synthesis and evaluation as transcarbamoylase inhibitors.
Flohr, A.; Aemissegger, A.; Hilvert, D. J. Med. Chem., 1999, 42, 2633-2640.
Electric fields in active sites: Substrate switching from null to strong fields in thiol- and selenosubtilisins.
Dinakarpandian, D.; Shenoy, B. C.; Hilvert, D.; McRee, D. E.; McTigue, M.; Carey, P. R. Biochemistry, 1999, 38, 6659-6667.
Stereoselective reactions with catalytic antibodies.
Hilvert, D. Topics in Stereochem., 1999, 22, 83-135.
An antibody-catalyzed allylic sulfoxide-sulfenate rearrangement.
Zhou, Z. S.; Flohr, A.; Hilvert, D. J. Org. Chem., 1999, 64, 8334-8341.
Evolution of shape complementarity and catalytic efficiency from a primordial antibody template.
Xu, J.; Deng, Q.; Chen, J.; Houk, K. N.; Bartek, J.; Hilvert, D.; Wilson, I. A. Science, 1999, 286, 2345-2348.
1997/98
Redesigning enzyme topology by directed evolution.
G. MacBeath, P. Kast & D. Hilvert, Science 1998, 279, 1958
Probing enzyme quaternary structure by combinatorial mutagenesis and selection
MacBeath G, Kast P, Hilvert D, Protein Science, 1998, 7(8), 1757-1767.
Exploring sequence constraints on an interhelical turn using in vivo selection for catalytic activity.
G. MacBeath, P. Kast & D. Hilvert, Protein Science 1998, 7, 325-335.
Selenosubtilisin's peroxidase activity does not require an intact oxyanion hole.
E.B. Peterson & D. Hilvert, Tetrahedron 1997, 53, 12311-12317.
An antibody-catalyzed selenoxide elimination.
Z.S. Zhou, N. Jiang & D. Hilvert, J. Am. Chem. Soc. 1997, 119, 3623-3624.
Up to 1997
Selection of a functional linker for a catalytic single-chain antibody using phage display technology.
Y. Tang, N. Jiang, C. Parakh & D. Hilvert, J. Biol. Chem. 1996, 271, 15682-15686.
Exploring the active site of chorismate mutase by combinatorial mutagenesis and selection: The importance of electrostatic catalysis.
P. Kast, M. Asif-Ullah, N. Jiang & D. Hilvert, Proc. Natl. Acad. Sci. USA 1996, 93, 5043-5048.
Nonessential active site residues modulate selenosubtilisin's kinetic mechanism.
E.B. Peterson & D. Hilvert, Biochemistry 1995, 34, 6616-6620.
Large rate accelerations in antibody catalysis by strategic use of haptenic charge.
S.N. Thorn, R.G. Daniels, M.-T.M. Auditor & D. Hilvert, Nature 1995, 373, 228-230.
Chemical synthesis of proteins.
D. Hilvert, Chemistry & Biology 1994, 1, 201-203.
Routes to catalysis: The structure of a catalytic antibody and comparison with its natural counterpart.
M.R. Haynes, E.A. Stura, D. Hilvert & I.A. Wilson, Science 1994, 263, 646-652.
